DMT is found as a minor alkaloid in snuff made from Virola bark resin in which 5-MeO-DMT is the main active alkaloid. It occurs as the primary psychoactive alkaloid in several plants including Mimosa tenuiflora, Diplopterys cabrerana, and Psychotria viridis. It is usually one of the main active constituents of the drink ayahuasca however, ayahuasca is sometimes brewed with plants that do not produce DMT. DMT-containing plants are commonly used in indigenous Amazonian shamanic practices. ( December 2022) ( Learn how and when to remove this template message)ĭMT is produced in many species of plants often in conjunction with its close chemical relatives 5-methoxy- N, N-dimethyltryptamine ( 5-MeO-DMT) and bufotenin (5-OH-DMT). You may improve this section, discuss the issue on the talk page, or create a new section, as appropriate. The examples and perspective in this section may not represent a worldwide view of the subject. Parts of the structure of DMT occur within some important biomolecules like serotonin and melatonin, making them structural analogs of DMT. ĭMT is a functional analog and structural analog of other psychedelic tryptamines such as O-acetylpsilocin (4-AcO-DMT), psilocybin (4-PO-DMT), psilocin (4-HO-DMT), O-methylbufotenin (5-MeO-DMT), and bufotenin (5-HO-DMT). DMT can produce vivid "projections" of mystical experiences involving euphoria and dynamic pseudohallucinations of geometric forms. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as the ayahuasca brew of many native Amazonian tribes. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. For those reasons, DMT was known as the "businessman's trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. ĭMT has a rapid onset, intense effects, and a relatively short duration of action. DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. N, N-Dimethyltryptamine ( DMT or N, N-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine.
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